CARDIOVASCULAR SYSTEM REACTION FEATURES OF STUDENTS WITH DIFFERENT TYPE OF BLOOD CIRCULATION AUTOREGULATION

  • V. Yu. Zadorozhnja Zaporizhzhya National University
  • O. Yu. Gavrilenko Zaporizhzhya National University
Keywords: students, heart rate, arterial pressure, systolic blood volume, stroke volume, blood circulation economization coefficient, type of blood circulation autoregulation

Abstract

The study aimed to determine peculiarities of cardiovascular system reaction in students with different type of blood circulation autoregulation.

The study took place at the physiology, immunology and biochemistry with a course in  civil defence and medicine department of the biological faculty in Zaporizhzhya national university, Zaporizhzhya. The participating Biological faculty students were examined in September/ October 2016 (2016-2017 academic year).

The total number of the examined female students was 30 students aged 19 to 21. The examination took place in the morning before the lectures time. All surveyed persons had no chronic diseases in anamnesis, or acute diseases/other bad health states during the tests.

Heart rate and arterial pressure were measured in all examined persons. The type of blood circulation autoregulation (TBCA) was defined in everyone surveyed on the gathered data basis.

ll surveyed persons were divided into 3 groups according to the TBCA. The vascular TBCA group was presented by 6 students (middle age 20,33 ± 0,21). The heart TBCA group included 13 students (middle age 20,46 ± 0,18), and the mixed TBCA group consisted of 11 students (middle age 20,27 ± 0,14). Anthropometric data and Quetelet index (QI) were defined in members of each group. To evaluate the degree of regulatory mechanisms tension primary indices, namely the arterial blood pressure (systolic and diastolic) and heart rate (HR) were measured. Further cardiovascular system indices (pulse arterial pressure, systolic blood volume, cardiac minute output, blood circulation economisation coefficient) were calculated from the measured indices. All indices were calculated using standard techniques.

The obtained results were processed using variation statistics methods in “Excel” with Student t-test employed for small samples. The minimum statistical significance was at р < 0,05.

Based on the conducted research results we established that among year four females heart TBCA (43 %) prevailed. Vascular TBCA (20 %) females were the smallest group. Females with mixed TBCA occupied intermediate position (37 %) between groups with heart and vascular TBCA.

Individual analysis of the QI estimate index has shown that among year four students with different TBCA persons with normal weight prevail: in the group of persons with vascular TBCA they constituted 83,3 %, in the group of students with heart TBCA ‒ 76,93 %, and in group with mixed TBCA – 81,82 %. Among year four students with different blood circulation autoregulation types persons with abnormally low weight constituted 15,38-18,8 % in each group. Overweight students were present only in a heart TBCA group totalling 7,69 %.

It has been established that the mean group HR indices in year four students with mixed and vascular ТBCA were within the norm, and in students with heart TBCA HR was 2,61 % above the norm. Average HR values in females with heart TBCA were significantly above 9,14 % (р < 0,05) those in students with mixed TBCA, and exceeded by 23,73 % (р < 0,001) the indices of heart reduction in females with vascular ТBСA. The highest mean group ATd indices were observed in students  with vascular ТBСA. These were higher than in students with heart TBCA by 11,47 % (р < 0,01), and 6,21 % above those in students with mixed ТBСA, but these distinctions were not statistically significant. The highest systolic blood volume indices were observed in students with heart TBCA: these were 14,12 % (р < 0,01) higher than in students with vascular ТBСA and 4,81 % higher as compared to the mixed ТBСA group. The lowest cardiac minute output indices were observed in a group of students with vascular ТBСA: these were 33,86 % (р < 0,001) lower than cardiac minute output indices in the heart ТBСA group. Cardiac minute output indices in females with mixed ТBСA were 23,15 % (р < 0,001) higher as compared to the vascular ТBСA group.

The largest percent of students which had the investigated indices within their age norm were in the mixed ТBСA group.. In the heart ТBСA group  students with elevated  HR (61,54 %) and APp (53,85 %) indices were prevalent. Systolic blood volume indices below the norm were prevalent in the vascular ТBСA group (83,33 %). 50 % of students with vascular ТBСA had cardiac minute output indices  within their age norm, while in in the other 50 % cardiac minute output was lower than the norm by 27,98 %.

Analysis of the mean group blood circulation economisation coefficient indices demonstrated that year four with heart ТBСA had these indices increased. Their blood circulation economisation coefficient values were 13,43 % above  norm, and 13,38 % (р < 0,05) above those in the mixed ТBСA group. This indicates a decrease in this groups cardiovascular system functional capacity and points at possible cardiovascular weariness and functional shortfalls. Mean group blood circulation economisation coefficient indices in females with vascular ТBСA were at the minimum and below the norm by 3,12 % which could indicate increased cardiovascular system and blood circulation efficiency.

References

ЛІТЕРАТУРА
1. Баевский Р. М., Берсенева А. П., Вакулин В. К. Оценка эффективности профилактических мероприятий на основе измерения адаптационного потенциала системы кровообращения. Здравоохранение Российской Федерации. 1987. № 8. С. 6-10.
2. Golbidi S., Laher I. Exercise and the Cardiovascular System. Hindawi Publishing Corporation Cardiology Research and Practice. 2012, Article ID 210852, 15 p. DOI:10.1155/2012/210852
3. Brooks G. A., Fahey T. D., White T. P. Exercise physiology: human bioenergetics and its applications. 2nd edition. Mountain View, CA: Mayfield Publishing Company, 1996. 346 р.
4. Гречкина Л. И. Особенности функционирования сердечно-сосудистой системы у мальчиков-подростков г. Магадана с разным типом саморегуляции кровообращения. Вестник СВНЦ ДВО РАН, 2015. № 1. С. 81–85.
5. Klabunde R. E. Cardiovascular Physiology Concepts. Lippincott Williams & Wilkins: Philadelphia. 2005. 256 p.
6. Patient-Specific Modeling of Cardiovascular Dynamics with a Major Role for Adaptation. Chapter 2 / Arts T. at.all. Patient-Specific Modeling of the Cardiovascular System: Technology-Driven Personalized Medicine, DOI 10.1007/978-1-4419-6691-9_2
7. Петров С. В. Особенности механизмов формирования типов саморегуляции кровообращения: автореф. дис. … канд. мед. наук 14.00.17 / Московская мед. академия им. И. М. Сеченова; Научно-исследовательский институт нормальной физиологии им. П.К. Анохина РАМН. Москва, 1996. 20 с.

8. Горячко А. Н., Адасько В. И. Оценка состояния центральной гемодинамики с использованием типов саморегуляции кровообращения у новорожденных младенцев, проживающих на загрязненных цезием-137 территориях. Режим доступа: http://www.iaea.org/inis/collection/NCLCollectionStore/_Public/29/049/29049418.pdf
9. Петров С. В. О вкладе частоты сердечных сокращений и систолического выброса крови в формирование минутного объема кровообращения. Вопросы экспериментальной и клинической физиологии. 2014. С. 246- 251.
10. Орлицкая Д. А., Погребняк Т. А. Особенности физиологической адаптации системы кровообращения у 11-15-летних школьников. Научный альманах. Биологические науки. 2016. № 7-2(21) С. 51-54
11. Хасанова Н. Н., Силантьев М. Н., Челышкова Т. В. Адаптивные возможности сердечно-сосудистой системы у студентов, работающих за компьютерами на занятиях по информатике в условиях профилактики утомления. Вестник АГУ. 2015. Вып. 2 (161). С. 73-79.
12. Жиженина Л. М., Кузнецова Т. А. Регуляция сердечно-сосудистой системы у студентов естественно-географического факультета Арзамасского филиала ННГУ разного возраста. Молодой учёный. Биология, химия, экология. 2015. № 23.2 (103.2). С. 127-129.
13. Аль Шаммари М. Я. И., Погребняк Т. А. Сравнительный анализ адаптации системы кровообращения у иностранных студентов в физиологических условиях. Сетевой научно-практический журнал. Научный результат. Серия Физиология. 2015. №1. С.48-55.
14. Борт Д. А., Ларькин В. И. Оптимизация методов диагностики синкопальных состояний с использованием провокационных проб. Омский научный вестник. Медицинские науки. 2013. №1 (118). С. 9-13.
15. Трифонов В. В. Особенности реакции кровообращения на ортостатическое влияние у лиц с разным типом саморегуляции кровообращения. Вопросы экспериментальной и клинической физиологии. 2014. С. 305-308.
16. Трифонов В. В. Особенности гемодинамики у лиц с сосудистым и сердечным типом саморегуляции кровообращения. Вестник Могилевского государственного ун-та. Сер. В, Естественные науки. 2014. №2(44). С. 90-95.
17. Лисова И. М. Адаптационные возможности и конституциональные особенности организма студентов разных климатогеографических регионов: дис. … канд. биол. наук 03.00.13 / Ставропольский государственный университет. Ставрополь, 2002. 241 с.
18. Статуева Л. М. Психофизиологическая адаптация старшеклассников и студентов к различным системам обучения: автореф. дис. … канд. биол. наук 03.00.13 / Нижегородский государственный университет им. Н. И. Лобачевского. Новгород. 2008. 22 с.
19. Аринчин Н. И. Комплексное изучение сердечно-сосудистой системы. Минск: Наука и техника, 1961. 220с.
20. Corley D. A., Kubo A. Body mass index and gastroesophageal reflux disease: a systematic review and meta-analysis. The American journal of gastroenterology. 2006. Т. 101, №. 11. P. 2619-2628.
21. Горобей М. П. Проблеми надлишкової ваги та ожиріння школярів і студентів. Педагогика, психологія та медико-біологічні проблеми фізичного виховання і спорту. 2012. № 5. С. 47-49.
22. Ясько Л. В. Оценка индекса массы тела у студентов специальной медицинской группы в процессе физического воспитания. Слобожанський науково-спортивний вісник. 2014. №2 (40). С. 135-138.
23. Духова Г. А. Методика определения и оценка функционального состояния сердечно-сосудистой системы: методические указания к практическим занятиям. М. : МИИТ, 2014. 25 с.
24. Морман Д. Хеллер Л. Физиология сердечно-сосудистой системы. СПб: Питер, 2000. 256 с.

REFERENCES
1. Baevskij R. M., Berseneva A. P., Vakulin V. K. Ocenka jeffektivnosti profilakticheskih meroprijatij na osnove izmerenija adaptacionnogo potenciala sistemy krovoobrashhenija. Zdravoohranenie Rossijskoj Federacii. 1987. № 8. S. 6-10.
2. Golbidi S., Laher I. Exercise and the Cardiovascular System. Hindawi Publishing Corporation Cardiology Research and Practice. 2012, Article ID 210852, 15 p. DOI:10.1155/2012/210852
3. Brooks G. A., Fahey T. D., White T. P. Exercise physiology: human bioenergetics and its applications. 2nd edition. Mountain View, CA: Mayfield Publishing Company, 1996. 346 r.
4. Grechkina L. I. Osobennosti funkcionirovanija serdechno-sosudistoj sistemy u mal’chikov-podrostkov g. Magadana s raznym tipom samoreguljacii krovoobrashhenija. Vestnik SVNC DVO RAN, 2015. № 1. S. 81–85.
5. Klabunde R. E. Cardiovascular Physiology Concepts. Lippincott Williams & Wilkins: Philadelphia. 2005. 256 p.
6. Patient-Specific Modeling of Cardiovascular Dynamics with a Major Role for Adaptation. Chapter 2 / Arts T. at. all. Patient-Specific Modeling of the Cardiovascular System: Technology-Driven Personalized Medicine, DOI 10.1007/978-1-4419-6691-9_2
7. Petrov S. V. Osobennosti mehanizmov formirovanija tipov samoreguljacii krovoobrashhenija: avtoref. dis. … kand. med. nauk 14.00.17 / Moskovskaja med. akademija im. I.M. Sechenova; Nauchno-issledovatel’skij institut normal’noj fiziologii im. P. K. Anohina RAMN. Moskva, 1996. 20 s.
8. Gorjachko A. N., Adas’ko V. I. Ocenka sostojanija central’noj gemodinamiki s ispol’zovaniem tipov samoreguljacii krovoobrashhenija u novorozhdennyh mladencev, prozhivajushhih na zagrjaznennyh ceziem-137 territorijah. Rezhim dostupa: http://www.iaea.org/inis/collection/NCLCollectionStore/_Public/29/049/29049418.pdf
9. Petrov S. V. O vklade chastoty serdechnyh sokrashhenij i sistolicheskogo vybrosa krovi v formirovanie minutnogo ob#ema krovoobrashhenija. Voprosy jeksperimental’noj i klinicheskoj fiziologii. 2014. S. 246- 251.
10. Orlickaja D. A., Pogrebnjak T. A. Osobennosti fiziologicheskoj adaptacii sistemy krovoobrashhenija u 11-15-letnih shkol’nikov. Nauchnyj al’manah. Biologicheskie nauki 2016 № 7-2(21) S. 51-54
11. Hasanova N. N., Silant’ev M. N., Chelyshkova T. V. Adaptivnye vozmozhnosti serdechno-sosudistoj sistemy u studentov, rabotajushhih za komp’juterami na zanjatijah po informatike v uslovijah profilaktiki utomlenija. Vestnik AGU. 2015. Vyp. 2 (161). S. 73-79.
12. Zhizhenina L. M., Kuznecova T. A. Reguljacija serdechno-sosudistoj sistemy u studentov estestvenno-geograficheskogo fakul’teta Arzamasskogo filiala NNGU raznogo vozrasta. Molodoj uchjonyj. Biologija, himija, jekologija. 2015. № 23.2 (103.2). S. 127-129.
13. Al’ Shammari M. Ja.I., Pogrebnjak T. A. Sravnitel’nyj analiz adaptacii sistemy krovoobrashhenija u inostrannyh studentov v fiziologicheskih uslovijah. Setevoj nauchno-prakticheskij zhurnal. Nauchnyj rezul’tat. Serija Fiziologija. 2015. №1. S.48-55.
14. Bort D. A., Lar’kin V. I. Optimizacija metodov diagnostiki sinkopal’nyh sostojanij s ispol’zovaniem provokacionnyh prob. Omskij nauchnyj vestnik. Medicinskie nauki. 2013. №1 (118). S. 9-13.
15. Trifonov V. V. Osobennosti reakcii krovoobrashhenija na ortostaticheskoe vlijanie u lic s raznym tipom samoreguljacii krovoobrashhenija. Voprosy jeksperimental’noj i klinicheskoj fiziologii. 2014. S. 305-308.
16. Trifonov V. V. Osobennosti gemodinamiki u lic s sosudistym i serdechnym tipom samoreguljacii krovoobrashhenija. Vestnik Mogilevskogo gosudarstvennogo un-ta. Ser. V, Estestvennye nauki. 2014. №2(44). S. 90-95.
17. Lisova I. M. Adaptacionnye vozmozhnosti i konstitucional’nye osobennosti organizma studentov raznyh klimatogeograficheskih regionov: dis. … kand. biol. nauk 03.00.13 / Stavropol’skij gosudarstvennyj universitet. Stavropol’, 2002. 241 s.
18. Statueva L. M. Psihofiziologicheskaja adaptacija starsheklassnikov i studentov k razlichnym sistemam obuchenija: avtoref. dis. … kand. biol. nauk 03.00.13 / Nizhegorodskij gosudarstvennyj universitet im. N. I. Lobachevskogo. Novgorod. 2008. 22 s.
19. Arinchin N. I. Kompleksnoe izuchenie serdechno-sosudistoj sistemy. Minsk: Nauka i tehnika, 1961. 220s.
20. Corley D. A., Kubo A. Body mass index and gastroesophageal reflux disease: a systematic review and meta-analysis. The American journal of gastroenterology. 2006. Т. 101, №. 11. P. 2619-2628.
21. Gorobej M. P. Problemi nadlishkovoї vagi ta ozhirіnnja shkoljarіv і studentіv. Pedagogika, psihologіja ta mediko-bіologіchnі problemi fіzichnogo vihovannja і sportu. 2012. № 5. S. 47-49.
22. Jas’ko L. V. Ocenka indeksa massy tela u studentov special’noj medicinskoj gruppy v processe fizicheskogo vospitanija. Slobozhans’kij naukovo-sportivnij vіsnik. 2014. №2 (40). S. 135-138.
23. Duhova G. A. Metodika opredelenija i ocenka funkcional’nogo sostojanija serdechno-sosudistoj sistemy: metodicheskie ukazanija k prakticheskim zanjatijam. M. : MIIT, 2014. 25 s.
24. Morman D. Heller L. Fiziologija serdechno-sosudistoj sistemy. SPb: Piter, 2000. 256 s.
How to Cite
Zadorozhnja, V. Y., & Gavrilenko, O. Y. (1). CARDIOVASCULAR SYSTEM REACTION FEATURES OF STUDENTS WITH DIFFERENT TYPE OF BLOOD CIRCULATION AUTOREGULATION. Bulletin of Zaporizhzhia National University. Biological Sciences, (2), 56-66. Retrieved from http://journalsofznu.zp.ua/index.php/biology/article/view/97