BIOCHEMICAL AND CLINICAL INDICATORS OF BLOOD WITH HYPERTENSION DISEASE

  • Ye. R. Fedotov Zaporizhzhya National University
  • I. P. Znak Zaporizhzhya National University
Keywords: arterial hypertension, arterial tissue, hypertonic disease, lipidogram, triglicerides, cholesterin, ischemic heart disease

Abstract

Hypertonic disease in our day is very common, especially in industrialized countries. Increased arterial pressure often occurs already in adolescence, the disease is rapidly young, like most diseases of the cardiovascular system.

Hypertensive disease and atherosclerosis are the most important cause of premature mortality. However, most often – this is a female problem. Two thirds of those who suffer from this illness are representatives of the fair sex.

Hypertensive disease – a common disease, which, according to widely accepted criteria, is sick, 15 % of the population. GC rarely occurs without symptoms, but is an important cause of disability and mortality, especially from cardiovascular disease. In about 95 % of cases, it is not possible to establish a specific cause of increased blood pressure. Such hypertension is called “essential”.

The human body is created with a large reserve of strength in the event of any situation. This also applies to the fluctuations in blood pressure and the strength of the vessels in this case. The vessel wall is able to withstand significant increases in pressure, provided it is sufficiently elastic and durable. Young people carry without any problems any physical and mental stress. With age, the elasticity of the vessels decreases, they can become “fragile and fragile”, with all the consequences of such changes.

Biochemical studies do not play any role in determining the diagnosis, but they are important for established causes of hypertension, especially in kidney disease and endocrine diseases.

The purpose of the work was to evaluate the informativeness of the biochemical and clinical parameters of blood with hypertension.

Research methods. Clinical research methods – determination of hemoglobin values, counting the number of red blood cells, leukocytes, platelets, determining the rate of erythrocyte sedimentation, determination of PIT, thrombin time. Biochemical methods of research – the calculation of blood glucose, creatinine and urea blood, cholesterol and triglycerides.

The novelty of the work is that for the first time the research of clinical and biochemical parameters of blood in patients with hypertonic disease of various degrees in unfavorable ecological conditions of the industrial region of Zaporizhzhya was carried out.

Indicators of the general analysis of blood, creatinine blood and coagulograms of patients with hypertension are within the normal limits and do not significantly differ from those of the control group.

Indicators of lipidograms (triglycerides and cholesterol), as well as blood sugar indexes in patients with hypertension exceed the upper limit of the norm and significantly differ from the control group.

In the analysis of blood parameters of patients with hypertonic disease of various degrees there is a significant increase in lipidogram (triglycerides and cholesterol), as well as blood sugar indexes in patients with hypertension II and III degrees.

The state of lipid metabolism in patients with GC and high levels of glucose may indicate a development of metabolic syndrome, which may lead to the development of type II diabetes, which requires immediate change in lifestyle (moderate physical activity with a rigid diet aimed at reducing body weight).

As a result of the work, it was found that in patients with hypertonic disease of various degrees there is a significant increase in lipidogram (triglycerides and cholesterol), as well as blood sugar indexes in patients with hypertension II and III degrees.

The state of lipid metabolism in patients with GC and high levels of glucose may indicate a development of metabolic syndrome, which may lead to the development of type II diabetes, which requires immediate change in lifestyle (moderate physical activity with a rigid diet aimed at reducing body weight).

The obtained results can be used by medical institutions for more sophisticated therapeutic treatment.

References

ЛІТЕРАТУРА
1. Литовский И. А., Гордиенко А. В. Атеросклероз и гипертоническая болезнь. Вопросы патогенеза, диагностики и лечения. Москва: Спец. лит., 2013. 312 с.
2. Аронов Д. М., Лупанов В. П. Атеросклероз и коронарная болезнь сердца. СПб.: Триада-X, 2014. 248 с.
3. Вейн А. М., Соловьева А. Д. Вегетативно-сосудистая дистония. Москва: Медицина, 2015. 317 с.
4. Давидкин И. Л., Куртов И. С., Хайретдинов Р. К. Болезни крови в амбулаторной практике. Москва: ГЭОТАР-Медиа, 2015. 192 с.
5. Верткин А. Л., Ховасова Н. О., Ларюшкина Е. Д., Шамаева К. И. Анемия: Руководство для практических врачей. Москва: ЭКСМО, 2014. 521 с.

REFERENCES
1. Litovski I. A., Gordienko A. V. Ateroskleroz i gipertonicheskaja bolezn’. Voprosy patogeneza, diagnostiki i lechenija. Moskva: Spec. lit., 2013. 312 s.
2. Aronov D. M., Lupanov V. P. Ateroskleroz i koronarnaja bolezn’ serdca. SPb.: Triada-X, 2014. 248 s.
3. Vejn A. M., Solov’eva A. D. Vegetativno-sosudistaja distonija. Moskva: Medicina, 2015. 317 s.
4. Davidkin I. L., Kurtov I. S. Hajretdinov R.K. Bolezni krovi v ambulatornoj praktike. Moskva: GJeOTAR-Media, 2015. 192 s.
5. Vertkin A. L., Hovasova N. O., Larjushkina E. D., Shamaeva K. I. Anemija: Rukovodstvo dlja prakticheskih vrachej. Moskva: JeKSMO, 2014. 521 s.
How to Cite
Fedotov, Y. R., & Znak, I. P. (1). BIOCHEMICAL AND CLINICAL INDICATORS OF BLOOD WITH HYPERTENSION DISEASE. Bulletin of Zaporizhzhia National University. Biological Sciences, (2), 98-103. Retrieved from http://journalsofznu.zp.ua/index.php/biology/article/view/102