СТАН СУГЛОБОВИХ ХРЯЩІВ ПРИ АРТРОЗІ ТА ПІСЛЯ ВВЕДЕННЯ ТЕСТ-ЗРАЗКА «ДРАСТОП»
Ключові слова:
артроз, хрящі, суглоби, щури, хондропротектори
Анотація
Встановлено, що при артрозі, індукованому введенням монойодацетату натрію в тканинах суглобових хрящів щурів спостерігаються патологічні дегенеративні зміни, характерні для аналогічного захворювання людини. Виявлено, що введення тест-зразка «Драстоп» відновлювало стан тканин хрящів тварин з артрозом.
Посилання
ЛІТЕРАТУРА
1. Osteoarthritis in the human knee: a dynamic process of cartilage matrix degradation, synthesis and reorganization / [Poole A.R., Rizkalla G., Ionescu M. et al.] //Agents and actions. Supplements. – 1992. – Vol. 39. – P. 3–13.
2. Development and pharmacological characterization of a rat model of osteoarthritis pain / [Pomonis J.D., Boulet J.M., Gottshall S.L. et al. ] // Pain. – 2005. – Vol. 114. – №. 3. – P. 339–346.
3. Strategy for the use of chondroprotectors in osteoarthrosis / [S.M. Noskov, A.A. Lavrukhina, K.Y. Shirokova et al.] // Terapevticheskii arkhiv. – 2012. – Vol. 85. – № 5. – P. 92–94.
4. Mescher A. Junqueira’s basic histology: text and atlas / A. Mescher. – McGraw-Hill, 2009. – 480 p.
5. Меркулов Г.А. Курс патологической техники / Г.А. Меркулов. – Л. : Медгиз, 1969. – 339 с.
6. Лили Р. Патогистологическая техника и практическая гистохимия / Р. Лили. – М. : Мир, 1969. – 646 c.
7. Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis / [R.E. Guzman, M.G. Evans, S. Bove et al.] // Toxicologic Pathology. – 2003. – Vol. 31, №. 6. – P. 619–624.
8. Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats / [K. Kobayashi, R. Imaizumi, H. Sumichika et al.] // Journal of Veterinary Medical Science. – 2003. – Vol. 65, №. 11. – P. 1195–1199.
9. Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivo from mono-iodoacetate (MIA)-induced chondrocytes death / [C. Cournil, B. Liagre, L. Grossin et al.] //Arthritis Research & Therapy. – 2001. – Vol. 3. – P. 1–1.
10. Knudson C.B. Cartilage proteoglycans / C.B. Knudson, W. Knudson // Seminars in cell & developmental biology. – Academic Press. – 2001. – Vol. 12, №. 2. – P. 69–78.
11. Pipitone V.R. Chondroprotection with chondroitin sulfate / V.R. Pipitone // Drugs under experimental and clinical research. – 1990. – Vol. 17, №. 1. – P. 3–7.
REFERENCES
1. Osteoarthritis in the human knee: a dynamic process of cartilage matrix degradation, synthesis and reorganization / [Poole A.R., Rizkalla G., Ionescu M. et al.] //Agents and actions. Supplements. – 1992. – Vol. 39. – P. 3–13.
2. Development and pharmacological characterization of a rat model of osteoarthritis pain / [Pomonis J.D., Boulet J.M., Gottshall S.L. et al. ] // Pain. – 2005. – Vol. 114, №. 3. – P. 339–346.
3. Strategy for the use of chondroprotectors in osteoarthrosis / [S.M. Noskov, A.A. Lavrukhina, K.Y. Shirokova et al.] // Terapevticheskii arkhiv. – 2012. – Vol. 85. – №. 5. – P. 92–94.
4. Mescher A. Junqueira’s basic histology: text and atlas / A. Mescher. – McGraw-Hill, 2009. – 480 p.
5. Merkulov G.A. Kurs patologicheskoj tehniki / G.A. Merkulov. – L. : Medgiz, 1969. – 339 p.
6. Lili R. Patogistologicheskaja tehnika i prakticheskaja gistohimija / R. Lili. – M. : Mir, 1969. – 646 p.
7. Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis / [R.E. Guzman, M.G. Evans, S. Bove et al.] // Toxicologic Pathology. – 2003. – Vol. 31, №. 6. – P. 619–624.
8. Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats / [K. Kobayashi, R. Imaizumi, H. Sumichika et al.] // Journal of Veterinary Medical Science. – 2003. – Vol. 65, №. 11. – P. 1195–1199.
9. Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivo from mono-iodoacetate (MIA)-induced chondrocytes death / [C. Cournil, B. Liagre, Grossin L. et al.] //Arthritis Research & Therapy. – 2001. – Vol. 3. – P. 1–1.
10. Knudson C. B., Knudson W. Cartilage proteoglycans //Seminars in cell & developmental biology. – Academic Press. – 2001. – V. 12, №. 2. – P. 69–78.
11. Pipitone V. R. Chondroprotection with chondroitin sulfate //Drugs under experimental and clinical research. – 1990.– Vol. 17, №. 1. – P. 3–7.
1. Osteoarthritis in the human knee: a dynamic process of cartilage matrix degradation, synthesis and reorganization / [Poole A.R., Rizkalla G., Ionescu M. et al.] //Agents and actions. Supplements. – 1992. – Vol. 39. – P. 3–13.
2. Development and pharmacological characterization of a rat model of osteoarthritis pain / [Pomonis J.D., Boulet J.M., Gottshall S.L. et al. ] // Pain. – 2005. – Vol. 114. – №. 3. – P. 339–346.
3. Strategy for the use of chondroprotectors in osteoarthrosis / [S.M. Noskov, A.A. Lavrukhina, K.Y. Shirokova et al.] // Terapevticheskii arkhiv. – 2012. – Vol. 85. – № 5. – P. 92–94.
4. Mescher A. Junqueira’s basic histology: text and atlas / A. Mescher. – McGraw-Hill, 2009. – 480 p.
5. Меркулов Г.А. Курс патологической техники / Г.А. Меркулов. – Л. : Медгиз, 1969. – 339 с.
6. Лили Р. Патогистологическая техника и практическая гистохимия / Р. Лили. – М. : Мир, 1969. – 646 c.
7. Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis / [R.E. Guzman, M.G. Evans, S. Bove et al.] // Toxicologic Pathology. – 2003. – Vol. 31, №. 6. – P. 619–624.
8. Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats / [K. Kobayashi, R. Imaizumi, H. Sumichika et al.] // Journal of Veterinary Medical Science. – 2003. – Vol. 65, №. 11. – P. 1195–1199.
9. Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivo from mono-iodoacetate (MIA)-induced chondrocytes death / [C. Cournil, B. Liagre, L. Grossin et al.] //Arthritis Research & Therapy. – 2001. – Vol. 3. – P. 1–1.
10. Knudson C.B. Cartilage proteoglycans / C.B. Knudson, W. Knudson // Seminars in cell & developmental biology. – Academic Press. – 2001. – Vol. 12, №. 2. – P. 69–78.
11. Pipitone V.R. Chondroprotection with chondroitin sulfate / V.R. Pipitone // Drugs under experimental and clinical research. – 1990. – Vol. 17, №. 1. – P. 3–7.
REFERENCES
1. Osteoarthritis in the human knee: a dynamic process of cartilage matrix degradation, synthesis and reorganization / [Poole A.R., Rizkalla G., Ionescu M. et al.] //Agents and actions. Supplements. – 1992. – Vol. 39. – P. 3–13.
2. Development and pharmacological characterization of a rat model of osteoarthritis pain / [Pomonis J.D., Boulet J.M., Gottshall S.L. et al. ] // Pain. – 2005. – Vol. 114, №. 3. – P. 339–346.
3. Strategy for the use of chondroprotectors in osteoarthrosis / [S.M. Noskov, A.A. Lavrukhina, K.Y. Shirokova et al.] // Terapevticheskii arkhiv. – 2012. – Vol. 85. – №. 5. – P. 92–94.
4. Mescher A. Junqueira’s basic histology: text and atlas / A. Mescher. – McGraw-Hill, 2009. – 480 p.
5. Merkulov G.A. Kurs patologicheskoj tehniki / G.A. Merkulov. – L. : Medgiz, 1969. – 339 p.
6. Lili R. Patogistologicheskaja tehnika i prakticheskaja gistohimija / R. Lili. – M. : Mir, 1969. – 646 p.
7. Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis / [R.E. Guzman, M.G. Evans, S. Bove et al.] // Toxicologic Pathology. – 2003. – Vol. 31, №. 6. – P. 619–624.
8. Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats / [K. Kobayashi, R. Imaizumi, H. Sumichika et al.] // Journal of Veterinary Medical Science. – 2003. – Vol. 65, №. 11. – P. 1195–1199.
9. Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivo from mono-iodoacetate (MIA)-induced chondrocytes death / [C. Cournil, B. Liagre, Grossin L. et al.] //Arthritis Research & Therapy. – 2001. – Vol. 3. – P. 1–1.
10. Knudson C. B., Knudson W. Cartilage proteoglycans //Seminars in cell & developmental biology. – Academic Press. – 2001. – V. 12, №. 2. – P. 69–78.
11. Pipitone V. R. Chondroprotection with chondroitin sulfate //Drugs under experimental and clinical research. – 1990.– Vol. 17, №. 1. – P. 3–7.
Як цитувати
Тіхова, Є. В., Дворщенко, К. О., Короткий, О. Г., Фалалєєва, Т. М., & Берегова, Т. В. (1). СТАН СУГЛОБОВИХ ХРЯЩІВ ПРИ АРТРОЗІ ТА ПІСЛЯ ВВЕДЕННЯ ТЕСТ-ЗРАЗКА «ДРАСТОП». Acta Biologica Ukrainica, (1), 99-105. вилучено із http://journalsofznu.zp.ua/index.php/biology/article/view/70
Розділ
ФІЗІОЛОГІЯ ЛЮДИНИ ТА ТВАРИН
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